Elias Arnérs forskargrupp

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Review: MAGYAR ONKOLOGIA. 2026;70(2):128-135
Context‑dependent targeting of thioredoxin reductase 1 in cancer: a mechanistic review.
Biri-Kovács B; Úri K; Andor A; Mohanraj M; Kolonics A; Pató ZA; Arnér ESJ
Article: ANTIOXIDANTS & REDOX SIGNALING. 2026;44(13-15):643-660
Thioredoxin 1 Suppresses TXNIP-Driven Control of Glucose Metabolism in Human Cells
Maimaiti S; Dagnell M; Coppo L; Zhao W; Geserick P; Kappert K; Arner ESJ
Article: APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2026;110(1):136
A katE katG double-knockout E. coli strain eliminates the risk of catalase contamination in recombinant proteins
Scholz AT; Coppo L; Nolan E; Hernandez M; Wang X; Mishra P; Schnell R; Pato ZA; Chen Y; Dagnell M; Andor A; Cheng Q; Arner ESJ
Article: SCIENCE ADVANCES. 2026;12(15):eadv5362
Intracellular enzymatic reducing systems control receptor tyrosine kinase signaling via PTP1B
Coppo L; Zhao W; Cheng Q; Scholz AT; Arner ESJ; Dagnell M
Review: CHEM. 2026;12(4):102868
A critical assessment of fluorescent probes as cellular reporters for thioredoxin system enzyme activities
Scholzen KC; Zeisel L; Arner ESJ
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2026;247:139-156
What lies beyond thioredoxin reductase? Cyclometallated gold compounds reveal Sec selectivity in glutathione peroxidases
Kanavos I; Nakahata DH; Barrett MS; Santos AFD; Zubiria-Ulacia M; Pieslinger GE; Teixeira ABDS; Medeiros I; Rocha CRR; Eberle J; Lobinski R; Matxain JM; Hall MD; Angeli JPF; Arner ESJ; Ronga L; De Paiva REF
Doctoral thesis: 2026
Towards single-cell resolution : exploring novel methods to study thioredoxin reductase
Scholzen K
Doctoral thesis: 2026
Dopaminergic regulation of basal ganglia synaptic transmission
Molinari M
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2025;241:689-706
Development of novel analogs of the TRi-1 and TRi-2 selenoprotein thioredoxin reductase inhibitors with initial assessment of their cytotoxicity profiles
Jovic M; Gencheva R; Scholzen KC; Cheng Q; Selakovic Z; Arner ESJ; Opsenica IM
Preprint: BIORXIV. 2025
Sodium Aurothiomalate Induces Ferroptosis by Targeting GPX4 via Gold-Dependent Thiomalate Covalent Modification
Hugo M; Gross L; Messias A; Alcober-Boquet L; Vignane T; Ghosh B; Aroua N; Denson L; Delgado-Martín S; Kaushal K; Yildiz U; Müller S; Martínez-Ruiz A; Estrin D; Augustin H; Rodriguez R; Biondi R; Trumpp A; Jayavelu AK; Cheng Q; Etzkorn M; Berndt C; Arnér ESJ; Filipovic M; Lella SD; Pastor-Flores D; Alborzinia H
Article: ANTIOXIDANTS. 2025;14(11):1351
Anti-Tumoral Treatment with Thioredoxin Reductase 1 Inhibitor Auranofin Fosters Regulatory T Cell and B16F10 Expansion in Mice
Bonner MY; Vancsik T; Oliveira-Coelho A; Sabatier P; Beusch CM; Zeqiraj K; Svensson C; Zubarev RA; Arner ESJ; Holmdahl R
Journal article: ANTIOXIDANTS. 2025;14(11):1351
Anti-Tumoral Treatment with Thioredoxin Reductase 1 Inhibitor Auranofin Fosters Regulatory T Cell and B16F10 Expansion in Mice.
Bonner MY; Vancsik T; Oliveira-Coelho A; Sabatier P; Beusch CM; Zeqiraj K; Svensson C; Zubarev RA; Arnér ESJ; Holmdahl R
Article: SCIENCE ADVANCES. 2025;11(45):eadx4577
Dopamine and serotonin cotransmission filters striatonigral synaptic activity via 5-HT1B receptor activation
Molinari M; Aaltonen A; Lieberman OJ; Sulzer D; Santini E; Borgkvist A
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2025;239:230-241
Patient-derived TXNIP-deficient primary cells exhibit NRF2 activation linked to upregulation of glyoxalase 1 (GLO1)
Maimaiti S; Dagnell M; Coppo L; Arner ESJ
Article: NATURE COMMUNICATIONS. 2025;16(1):8307
An injury-associated lobular microniche is associated with the classical tumor cell phenotype in pancreatic cancer
Soderqvist S; Viljamaa A; Geyer N; Keller A-L; Ruksha K; Strell C; Hekmati N; Niculae A; Engstrand J; Sparrelid E; Salmen C; Costa TDF; Zhao M; Stromblad S; Zacharouli A; Ghorbani P; Harrizi S; Hamidi Y; Khorosjutina O; Milanova S; Schmierer B; Bozoky B; Fernandez Moro C; Gerling M
Article: REDOX BIOLOGY. 2025;85:103741
The inhibition of TXNRD1 by methylglyoxal impairs the intracellular control of Mycobacterium tuberculosis
Li H; Liu R; Kathamuthu GR; Gencheva R; Gong Z; Scholz AT; Alzrigat M; Coppo L; Arner ESJ; Rottenberg ME
Journal article: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2025;137(35)
Bicyclic Selenenyl Sulfides with Tuned Bioreductive Step Rates Reveal Constraints for Probes Targeting Thioredoxin Reductase
Zeisel L; Weissenhorn LD; Scholzen KC; Madabeni A; Orian L; Arnér ESJ; Thorn‐Seshold O
Article: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2025;64(35):e202508911
Bicyclic Selenenyl Sulfides with Tuned Bioreductive Step Rates Reveal Constraints for Probes Targeting Thioredoxin Reductase
Zeisel L; Weissenhorn LD; Scholzen KC; Madabeni A; Orian L; Arner ESJ; Thorn-Seshold O
Article: G3-GENES GENOMES GENETICS. 2025;15(8):jkaf102
The transsulfuration pathway suppresses the embryonic lethal phenotype of glutathione reductase mutants in Caenorhabditis elegans
Valenzuela-Villatoro M; Gomez-Orte E; Guerrero-Gomez D; Cheng Q; Zheleva A; Mora-Lorca JA; Petrovic D; O'Neil NJ; Ceron J; Hatakeyama A; Onami S; Ordonez-Luque A; Ayuso C; Askjaer P; Filipovic MR; Arner ESJ; Cabello J; Miranda-Vizuete A
Article: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. 2025;1872(6):119967
Clozapine blunts mitochondrial biogenesis in differentiating adipocytes: The increased ATP demand is met via stimulation of electron transport chain expression and activity in residual mitochondria
Fiorani M; Buffi G; Bagherlou N; Canonico B; De Matteis R; Guidarelli A; Montanari M; Battistelli M; Papa S; Coppo L; Cerioni L; Spina A; Cantoni O
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