Clinical and translational breast cancer research – Alexios Matikas' team

Publications

All publications from group members

• Journal article: EUROPEAN JOURNAL OF CANCER. 2026;245:116937

  Chemotherapy type and survival in young BRCA1/2 carriers with HER2-negative early breast cancer

  Bernstein-Molho R; Sella T; Delucchi V; Coussy F; Kim HJ; Linn S; Di Meglio A; Pogoda K; Kwong A; Agostinetto E; Bajpai J; Van Herck Y; Ferrari A; Balmana J; Moore HCF; Peccatori FA; Partridge AH; Winocur M; Renaud T; Rousset-Jablonski C; Lee JE; Toss A; Paluch-Shimon S; Wong SM; Matikas A; Ac CV-G; Vernieri C; Lee M; Guven DC; Cui W; Ruddy KJ; Dieci MV; Fruscio R; De Marchis L; Kemp Z; Meireles PA; Razeti MG; Diz MDP; Hwang SE; Puglisi F; Clatot F; Yerushalmi R; Cichowska-Cwalinska N; Chirco A; De Angelis C; Blondeaux E; Lambertini M
• Article: BREAST. 2026;88:104834

  A nationwide population-based study on the incidence and prognosis of HER2-positive breast cancer eligible for adjuvant pertuzumab in the modern era of neoadjuvant therapy

  Valachis A; Liu X; Acs B; Hartman J; Foukakis T; Matikas A
• Article: NATURE COMMUNICATIONS. 2026;17(1):8235

  Risk stratification and relapse pattern in triple-negative breast cancer with pathological complete response after neoadjuvant treatment: the European GAMBIT real-world study

  Massa D; Foukakis T; Giacchetti S; Desmedt C; Frenel J-S; Gasparini E; Kok M; Vigneri P; Jacot W; Vernieri C; Lambertini M; Patane F; Piacentini F; Bria E; Zambelli A; Trapani D; Botticelli A; Garrone O; Lando S; Matikas A; Someil L; Floris G; Campone M; Ragazzi M; Lips E; Martorana F; Bonomi G; Papakonstantinou A; Nicole L; Zerdes I; Neven P; Rotolo M; Horlings H; Nucera S; Gudin-De-Vallerin A; Vingiani A; Dei Tos AP; Guarneri V; Dieci MV
• Article: RADIOTHERAPY AND ONCOLOGY. 2026;219:111523

  Radiation therapy management in BRCA1/2 carriers diagnosed with early breast cancer: An international cohort study

  Becherini C; Blondeaux E; Delucchi V; Visani L; Kim HJ; Coussy F; Bernstein-Molho R; Di Meglio A; Hilbers FS; Pogoda K; Kwong A; Agostinetto E; Baten A; Bajpai J; Balmana J; Moore HCF; Partridge AH; Rousset-Jablonski C; Phillips K-A; Toss A; Renaud T; Ferrari A; Peccatori FA; Sanchez L; Paluch-Shimon S; Cui W; Wong SM; Ryu JM; Fruscio R; Lee MK; Vernieri C; Matikas A; Couch FJ; De Marchis L; Dieci MV; Aguilar-Y-Mendez D; Hwang SE; Rozenblit M; Guven DC; Mrinakova B; Harbeck N; Sanchez-Bayona R; Boni L; Lambertini M; Meattini I
• Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2026;44(16_SUPPL):e12508

  A nationwide population-based study on the incidence and prognosis of patients with HER2+breast cancer eligible for adjuvant pertuzumab in the modern era of neoadjuvant therapy.

  Matikas A; Liu X; Acs B; Hartman J; Foukakis T; Valachis A
• Article: EUROPEAN JOURNAL OF CANCER. 2026;239:116699

  Integrating liquid biopsies and artificial intelligence for early cancer detection: A systematic review and meta-analysis

  Filis P; Markozannes G; Salgkamis D; Tsiknakis N; Zerdes I; Pagkalidou E; Manou M; Filis N; Papakonstantinou A; Mavroudis D; Matikas A; Tsilidis KK; Foukakis T
• Review: JOURNAL OF INTERNAL MEDICINE. 2026;299(5):538-569

  Perioperative immune checkpoint inhibitor therapy across tumors: Insights and shared lessons from a rapidly evolving field

  Bjorkstrom K; Matikas A; Svedman FC; Bjorgvinsson E; Zupancic M; Villabona L; Eriksson H; Skribek M; Fernebro J; Lindskog M; Frodin J-E; Ullen A; Ekman S; Helgadottir H
• Article: ESMO OPEN. 2026;11(5):107696

  Concordance between clinician-reported toxicities and patient-reported symptom severity in early-stage breast cancer: an analysis of the randomized phase III PANTHER trial

  Filis P; Liu X; Matikas A; Untch M; Steger GG; Johansson H; Hellstrom M; Gnant M; Loibl S; Brandberg Y; Bergh J; Foukakis T
• Article: NATURE COMMUNICATIONS. 2026;17(1):3403

  Neoadjuvant palbociclib and endocrine therapy versus chemotherapy in ER + /HER2-breast cancer: a randomized phase II trial

  Matikas A; Tzoras E; Sarafidis M; Sifakis EG; Bjohle J; Barnekow E; Margolin S; Isaksson-Friman E; Kessler LE; Zouzos A; Johansson H; Hellstrom M; Agartz S; Gryback P; Salgkamis D; Zerdes I; Wang K; Hartman J; Acs B; Sun W; Boyaci C; Villacampa G; Pascual T; Gavila J; Prat A; Perou C; Brandberg Y; Bergh J; Hatschek T; Foukakis T
• Journal article: CANCER RESEARCH. 2026;86(7):3527

  Clonal evolutionary trajectory of HER2-positive breast cancer with ERBB2 or PIK3CA mutations under neoadjuvant treatment

  Wang K; Zerdes I; Sifakis EG; Salgkamis D; Bergh J; Hatschek T; Matikas A; Foukakis T
• Article: ANNALS OF ONCOLOGY. 2026;37(3):364-377

  Association between type and location of germline BRCA1/2 pathogenic or likely pathogenic variants with phenotype and prognosis in young patients with breast cancer: results from an international cohort study

  Toss A; Blondeaux E; Tenedini E; Bonamici L; Graffeo R; Livraghi L; Villarreal-Garza C; Molho RB; Kwong A; Balmana J; Wildiers H; Agostinetto E; Phillips KA; Pogoda K; Renaud T; Rousset-Jablonski C; Ferrari A; Moore HCF; Peccatori FA; Paluch-Shimon S; Fruscio R; Micheri C; Wong SM; Cui W; Vernieri C; Lee MK; De Marchis L; Couch FJ; Del Mastro L; Puglisi F; Meireles PA; Kemp Z; Matikas A; Plichta J; Del Pilar Estevez-Diz M; Di Meglio A; Cichowska-Cwalinska N; Gianni C; Yerushalmi R; Sanchez-Bayona R; Mrinakova B; Matos L; Bianchini G; Caleffi M; Krivokuca A; Abdou Y; Marino-Marino M; Parokonnaya A; Okano M; Antone N; Saavedra C; Sonnenblick A; Duchnowska R; Pais HL; Harbeck N; Cortesi L; Delucchi V; De Angelis C; Lambertini M
• Journal article: CLINICAL CANCER RESEARCH. 2026;32(4_Supplement):ps4-12-24-ps4-12-24

  Abstract PS4-12-24: Risk and Pattern of Relapse in Triple-Negative Breast Cancer with Pathological Complete Response after Neoadjuvant Treatment: Updated Results from the European GAMBIT Real-world Study

  Dieci M; Foukakis T; Giacchetti S; Desmedt C; Frenel J; Gasparini E; Kok M; Vigneri P; Jacot W; Vernieri C; Lambertini M; Patanè F; Piacentini F; Bria E; Zambelli A; Trapani D; Botticelli A; Garrone O; Massa D; Lando S; Matikas A; Someil L; Floris G; Campone M; Ragazzi M; Lips E; Martorana F; Bonomi G; Papakostantinou A; Nicolé L; Zerdes I; Neven P; Rotolo M; Horlings H; Nucera S; Gudin de Vallerin A; Vingiani A; Tos AD; Guarneri V
• Journal article: CLINICAL CANCER RESEARCH. 2026;32(4_Supplement):pd4-07-pd4-07

  Abstract PD4-07: Association between age at diagnosis and survival among young BRCA carriers with breast cancer: results from an international multicenter hospital-based cohort study

  Blondeaux E; Meacci A; Gil MF; Klocker E; Coussy F; Kim H; Molho RB; Hilbers F; Di Meglio A; Kwong A; Pogoda K; Bajpai J; Wildiers H; Agostinetto E; Balmana J; Moore HC; Phillips K; Partridge AH; Rousset-Jablonski C; Peccatori FA; Toss A; Renaud T; Anghelone C; Cruz AB; Paluch-Shimon S; Lee J; Fruscio R; Cui W; Wong SM; Lee M; Rozenblit M; Vernieri C; Villarreal-Garza C; Matikas A; Dieci M; De Marchis L; Plichta JK; Ruddy KJ; Guven DC; Puglisi F; Kemp Z; Meireles PA; Del Mastro L; Delucchi V; Lambertini M
• Journal article: CLINICAL CANCER RESEARCH. 2026;32(4_Supplement):pd12-01-pd12-01

  Abstract PD12-01: Surgical management of young BRCA1/2 carriers with early onset breast cancer

  Wong SM; Blondeaux E; Delucchi V; Coussy F; Molho RB; Linn S; Di Meglio A; Kwong A; Pogoda K; Agostinetto E; Nevelsteen I; Balmana J; Moore HC; Toss A; Ferrari A; Rousset-Jablonski C; Renaud T; Phillips K; PeccatorI FA; Ipina MA; Paluch-Shimon S; Ryu J; Kui W; Lee M; Fruscio R; Rozenblit M; Vernieri C; Matikas A; Dieci M; Couch FJ; De Marchis L; Hwang SE; Mendez DA-Y; Guven DC; Swain M; Gianni C; Spinaci S; Montagna G; Lambertini M; Kim H
• Journal article: CLINICAL CANCER RESEARCH. 2026;32(4_Supplement):ps2-08-01-ps2-08-01

  Abstract PS2-08-01: A predictive gene signature for benefit from dose-dense adjuvant chemotherapy in patients with high-risk early breast cancer: results from the PANTHER phase III trial

  Salgkamis D; Sarafidis M; Sifakis E; Zerdes I; Agartz S; Hartman J; Hellström M; Foukakis T; Bergh J; Matikas A
• Conference publication: CLINICAL CANCER RESEARCH. 2026;32

  Risk and Pattern of Relapse in Triple-Negative Breast Cancer with Pathological Complete Response after Neoadjuvant Treatment: Updated Results from the European GAMBIT Real-world Study

  Dieci M; Foukakis T; Giacchetti S; Desmedt C; Frenel J; Gasparini E; Kok M; Vigneri P; Jacot W; Vernieri C; Lambertini M; Patane F; Piacentini F; Bria E; Zambelli A; Trapani D; Botticelli A; Garrone O; Massa D; Lando S; Matikas A; Someil L; Floris G; Campone M; Ragazzi M; Lips E; Martorana F; Bonomi G; Papakostantinou A; Nicole L; Zerdes I; Neven P; Rotolo M; Horlings H; Nucera S; de Vallerin AG; Vingiani A; Tos AD; Guarneri V
• Conference publication: CLINICAL CANCER RESEARCH. 2026;32

  Association between age at diagnosis and survival among young BRCA carriers with breast cancer: results from an international multicenter hospital-based cohort study

  Blondeaux E; Meacci A; Gil MF; Klocker E; Coussy F; Kim H; Molho RB; Hilbers F; Di Meglio A; Kwong A; Pogoda K; Bajpai J; Wildiers H; Agostinetto E; Balmana J; Moore HC; Phillips K; Partridge AH; Rousset-Jablonski C; Peccatori FA; Toss A; Renaud T; Anghelone C; Cruz AB; Paluch-Shimon S; Lee J; Fruscio R; Cui W; Wong SM; Lee M; Rozenblit M; Vernieri C; Villarreal-Garza C; Matikas A; Dieci M; De Marchis L; Plichta JK; Ruddy KJ; Guven DC; Puglisi F; Kemp Z; Meireles PA; Del Mastro L; Delucchi V; Lambertini M
• Conference publication: CLINICAL CANCER RESEARCH. 2026;32

  Surgical management of young BRCA1/2 carriers with early onset breast cancer

  Wong SM; Blondeaux E; Delucchi V; Coussy F; Molho RB; Linn S; Di Meglio A; Kwong A; Pogoda K; Agostinetto E; Nevelsteen I; Balmana J; Moore HC; Toss A; Ferrari A; Rousset-Jablonski C; Renaud T; Phillips K; Peccator FAI; Ipina MA; Paluch-Shimon S; Ryu J; Kui W; Lee M; Fruscio R; Rozenblit M; Vernieri C; Matikas A; Dieci M; Couch FJ; De Marchis L; Hwang SE; Aguilar-y Mendez D; Guven DC; Swain M; Gianni C; Spinaci S; Montagna G; Lambertini M; Kim H
• Conference publication: CLINICAL CANCER RESEARCH. 2026;32

  A predictive gene signature for benefit from dose-dense adjuvant chemotherapy in patients with high-risk early breast cancer: results from the PANTHER phase III trial

  Salgkamis D; Sarafidis M; Sifakis E; Zerdes I; Agartz S; Hartman J; Hellstrom M; Foukakis T; Bergh J; Matikas A
• Article: ESMO OPEN. 2026;11(2):106062

  Progression-free survival 2 (PFS2) as a surrogate endpoint for overall survival (OS) in breast cancer randomized controlled clinical trials

  Filis P; Filis N; Foukakis T; Matikas A
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Funding

Staff and contact

Group leader

• 

  Alexios Matikas

  Affiliated to Research | Associate Professor

  E-mail alexios.matikas@ki.se

All members of the group

• Caroline Boman

  Phd Student

  E-mail caroline.boman@ki.se
• Behnaz Binicy

  Affiliated to Research

  E-mail behnaz.khalilzadehbinicy@ki.se
• Xingrong Liu

  Statistician

  E-mail xingrong.liu@ki.se
• 

  Dimitrios Salgkamis

  Clinical Assistant

  E-mail dimitrios.salgkamis@ki.se
• 

  Michail Sarafidis

  Postdoctoral Researcher

  E-mail michail.sarafidis@ki.se